CSC news roundup 2010-01-31

• Hypoxia inducible factors in CSC [FriendFeed entry] [Connotea bookmark]


• Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer [FriendFeed entry] http://is.gd/73pVk


• Evidence for self-renewing lung cancer stem cells and their implications [FriendFeed entry] [Connotea bookmark]


• The elaboration of a critical framework for understanding cancer: the CSC hypothesis [FriendFeed entry][Connotea bookmark]


• IMUC’s ICT-107 vaccine product candidate targets CSC [FriendFeed entry] http://bit.ly/5BnV5q


• Putative CSC markers show strong prognostic significance in colorectal cancer [FriendFeed entry][Connotea bookmark] http://bit.ly/7uUuOZ


• Cell of Origin Identified for Common Type of Breast Cancer [FriendFeed entry] http://bit.ly/4B0GOl http://bit.ly/5n9Icz


• Cancer Biomarker Chase Accelerates [FriendFeed entry] http://bit.ly/57iVWN


• CSC suppress immune response against brain tumor [FriendFeed entry] http://bit.ly/6HgW1g


• About a new report: Targeting CSC: Therapeutic Strategies and Pipeline Developments [FriendFeed entry] http://bit.ly/8mfqET


• More evidence that tumours, like healthy organs, grow from SC. The Economist, 14 Jan 2010 [FriendFeed entry] http://bit.ly/4AeekG


• AC133 Epitope, but not the CD133 Protein, Is Lost upon CSC differentiation [FriendFeed entry] http://bit.ly/6r2aGh


• Nanosystems capture and destroy circulating tumor cells (CTC) [FriendFeed entry] http://bit.ly/7ebzXI


• Evidence that CSC escape and down-regulate host antitumor immunity [FriendFeed entry] http://bit.ly/5vWN8n http://bit.ly/5wgRBV


• Stem cells linked to an aggressive cancer of childhood [FriendFeed entry] http://bit.ly/73ldYl http://bit.ly/6YaniV


• Role for the SCF-c-kit signaling axis in self-renewal and proliferation of human lung CSC [FriendFeed entry] http://bit.ly/6PxEyW


• High-throughput screening of tumor-initiating cells in zebrafish [FriendFeed entry] http://bit.ly/6G06No


• The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells [FriendFeed entry] http://icio.us/t0td2z


• OncoMed, Fluidigm to Analyze Tumor Cell Populations [FriendFeed entry] http://bit.ly/7GnYvm


• Therapy which fails to target CSC can actually promote malignant features in the recurring tumor! [FriendFeed entry] http://bit.ly/6h7jOp


• CXCR1 blockade selectively targets human breast CSC in vitro and in xenografts [FriendFeed entry] http://bit.ly/69ynfK